Relatively high diagnostic sensitivity and specificity for glaucoma detection has been demonstrated using time-domain OCT (TD-OCT) and spectral-domain OCT (SD-OCT) RFNL thickness measurements. With the advent of optical coherence tomography (OCT), cross-sectional imaging of the RNFL has improved detection of damage to the RNFL. ![]() Another limitation is the difficulty in obtaining fundus photographs with sufficient quality for interpretation, especially in eyes with a hypopigmented fundus or myopia, when background reflection is high and contrast is low. Although red-free fundus photography is the standard approach for examining the RNFL, changes in the RNFL are often not detectable until there is more than 50% nerve fiber loss. Evaluation of the retinal nerve fiber layer (RNFL) is crucial for detecting and managing glaucoma, which is a progressive optic nerve disease characterized by a loss of the RNFL. The sensory retina is composed of nine contiguous layers, linked to each other by synaptic connections. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors. There are no patents, products in development or marketed products to declare. TI is an employee of Hamamatsu Photonics. Hangai and NY are paid members of the advisory board of NIDEK and S. ![]() The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: Supported by a grant from the New Energy and Industrial Technology Development Organization (P05002), Kawasaki, Japan. Received: AugAccepted: FebruPublished: March 12, 2012Ĭopyright: © 2012 Takayama et al. PLoS ONE 7(3):Įditor: Celia Oreja-Guevara, University Hospital La Paz, Spain ![]() (2012) High-Resolution Imaging of the Retinal Nerve Fiber Layer in Normal Eyes Using Adaptive Optics Scanning Laser Ophthalmoscopy. Citation: Takayama K, Ooto S, Hangai M, Arakawa N, Oshima S, Shibata N, et al.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |